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Dr. Capuano is an experienced synthetic medicinal chemist specializing in the design, synthesis, and biological evaluation of small biomolecules targeting G protein-coupled receptors implicated in schizophrenia and Parkinson's disease. His research also focuses on analogues of opium poppy-derived alkaloid noscapine as novel anticancer agents, allosteric modulators of central muscarinic receptors for potential treatment of Alzheimer's disease, and fragment-based drug discovery for novel inhibitors of enzymes like DsbA and HIV-integrase. His specific expertise includes solution and solid-phase organic synthesis, comprehensive chemical purification and characterization, and knowledge of molecular modeling techniques including virtual screening and molecular docking. Dr. Capuano also provides training in in vitro, functional, and behavioral assays.
Monash University • Australia
Teaching and research in the Faculty of Pharmacy and Pharmaceutical Sciences, focusing on medicinal chemistry and drug design.
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