Dr. Benoit Coulombe

Biography

Benoit Coulombe is a Professor and leading researcher at the Université de Montréal, specializing in Health Sciences and Medical Sciences. His research lab focuses on understanding the mechanisms regulating gene transcription by RNA polymerase II in mammals. The mammalian genome comprises around 30,000 genes, whose expression is tightly controlled, enabling cell growth and differentiation. His work delves into the complex process where RNA polymerase II recognizes gene promoters and catalyzes the transcription of DNA into RNA, involving numerous interactions with the DNA template, the RNA in synthesis, and various regulatory proteins. Dr. Coulombe's lab employs advanced technologies in molecular biology, biochemistry, genomics, proteomics, and bioinformatics to uncover the intricate regulatory mechanisms related to transcription. He holds significant educational responsibilities, supervising both doctoral and master’s students in a variety of projects that explore cellular heterogeneity and protein interactions within transcription machinery. Dr. Coulombe's influential role in collaborative research projects and funding initiatives reflects his commitment to advancing scientific understanding in his field.

Research Interests

Experience