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Bernd Helms studies intracellular membrane dynamics in mammalian cells, with major expertise in protein lipid biochemistry. His current research focuses on lipid and membrane dynamics, applying lipidomic techniques to study the function of lipids and lipid droplets in the pathogenesis of veterinary and human diseases. The understanding of biological membrane dynamics has evolved dramatically over the decades, moving from the initially static model proposed by Singer and Nicholson to a view that sees membranes as highly dynamic structures where continuous transport and organelle interaction play key roles. His research aims to understand the dynamic properties of biological membranes and their crucial roles in normal cell physiology and in diseases resulting from dysfunctional membrane dynamics. Key research areas include the dynamics of lipid droplets in the liver, the transport functions of vitamins such as retinoids, the role of membranes and lipids in protein oligomerization, and the dynamics of sperm-oocyte membrane fusion during fertilization. Helms collaborates with national and international biochemical, biomedical, and cell biological research groups to provide a molecular basis for understanding diseases and developing new strategies to create novel drugs for the benefit of human and animal health.
Department of Psychology