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Bernhard Wehrle-Haller leads a research group at the Centre Médical Universitaire where he focuses on the mechanisms of cell adhesion, migration, and extracellular matrix remodeling. His work employs cell biological and life-cell imaging techniques to understand the roles of growth factors and extracellular matrix proteins, such as fibronectin, laminin, and vitronectin, and their interaction with receptor systems like integrins. He investigates how the physical and biochemical properties of the extracellular matrix influence cellular behaviors, including adhesion and migration, particularly in the context of cancer metastasis and tissue fibrosis. His research aims to reveal critical signaling steps that control these processes and explore potential therapeutic targets to counteract pathological conditions related to tissue remodeling. Additionally, his group studies the mechanosensing capabilities of cells and how their microenvironment impacts their survival and response to therapeutic interventions.
Includes Department of Management, Finance, Economics, and Statistics programs. GMAT is strongly encouraged but not mandatory for most GSEM masters.