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Dr. Bin Zhou's laboratory focuses on the factors and mechanisms that control heart and coronary vessel development, seeking insights into the pathogenesis of congenital heart disease. The research employs mouse models and human stem cells, utilizing an integrated approach that combines genetics, developmental biology, and advanced technologies including single-cell techniques and CRISPR gene editing. Major research questions explore the specification, maintenance, and diversification of cardiac cell lineages, communications that modulate cardiac function under various conditions, and the reactivation of fetal cardiac gene programs in diseased hearts. His work has substantial implications for understanding and potentially repairing congenital and acquired heart diseases.
University of Chicago • Chicago, IL
Conducting research and teaching in the field of Pediatrics with a focus on heart development and disease.
Department of Philosophy