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Blas Frangione is a Research Professor at New York University specializing in the molecular basis of Alzheimer's disease (AD), a neurodegenerative disorder characterized by progressive mental deterioration in late life. His research delves into the biochemical events leading to brain degeneration, particularly focusing on the deposition of abnormal amyloid beta protein in the brain's parenchyma and cerebral vessel walls. He has identified hereditary cerebral hemorrhage associated with amyloidosis in patients of Dutch origin, as well as the genetic components influencing familial forms of AD. His current research includes investigating gene mutations associated with familial Alzheimer's disease (FAD), exploring the biochemical relationship between apolipoprotein E and AD, and developing animal models to study the mechanisms of amyloid deposition. Frangione's contributions to the field have significantly advanced the understanding of the genetic and biochemical factors involved in Alzheimer's disease.
Open Program in Biomedical Sciences (Vilcek Institute) covers departments like Biochemistry, Pathology, Neuroscience, Microbiology, etc.