Dr. Bluma Lesch

Biography

Bluma Lesch works on mechanisms of transcriptional regulation in developmental contexts, evolution, and disease, with a special interest in genetics and epigenetics related to mammalian germ line. Her research integrates information across a wide range of biological scales, from molecular mechanisms to organismal development and species evolution, utilizing both experimental and computational approaches. Current projects focus on uncovering the rules governing gene regulatory evolution, defining transgenerational epigenetic contributions to offspring phenotype, and employing unique regulatory biology of the germ line to discover fundamental gene regulatory mechanisms that can go awry in disease. Dr. Lesch earned her B.S. from Yale University in 2003, followed by a Ph.D. from Rockefeller University in 2010 and an M.D. from Weill Cornell Medical College in 2011. She completed her postdoctoral fellowship at the Whitehead Institute from 2011-2017, where she was awarded the NIH Kirschstein postdoctoral fellowship and named a Hope Funds Cancer Research postdoctoral fellow. Dr. Lesch has received the Burroughs Wellcome Career Award for Medical Scientists in 2015 and joined the faculty at Yale in 2017. She has been recognized as a Searle Scholar in 2019 and a Pew Biomedical Scholar in 2021.

Research Interests

Awards