Dr. Bluma Lesch

Biography

Bluma Lesch works on mechanisms of transcriptional regulation in the context of development, evolution, and disease, with a special interest in genetics and epigenetics. Her research integrates information across a wide range of biological scales, exploring molecular mechanisms, organismal development, and species evolution using both experimental and computational approaches. Current projects focus on uncovering rules of gene regulatory evolution, defining transgenerational epigenetic contributions to offspring phenotype, and using unique regulatory biology of the germ line to discover fundamental gene regulatory mechanisms that go awry in disease. She earned her B.S. from Yale University in 2003, obtained her Ph.D. in 2010 from Rockefeller University, and an M.D. in 2011 from Weill Cornell Medical College in New York City. She was a postdoctoral fellow at the Whitehead Institute from 2011 to 2017 and was awarded the NIH Kirschstein postdoctoral fellowship and named a Hope Funds Cancer Research postdoctoral fellow. In 2015, she received the Burroughs Wellcome Career Award in Medical Scientists, returning to New Haven to join the Yale faculty in 2017, and has been recognized as a Searle Scholar in 2019 and a Pew Biomedical Scholar in 2021.

Research Interests

Awards