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Bogyo Lab is dedicated to the development and application of chemical tools to explore the functional roles of hydrolases in various human health conditions. The research group comprises synthetic organic chemists, biologists, biochemists, and cell biologists working collaboratively with methods including synthetic chemistry and phage display. The lab's primary research focuses on several key areas: the development of proteasome inhibitors aimed at treating malaria caused by the human parasite Plasmodium falciparum; identification of novel serine hydrolase targets in pathogenic bacteria such as Staphylococcus aureus and Mycobacterium tuberculosis; and the exploration of proteases that regulate bacterial signaling and survival within gut commensal microbes. Additionally, Bogyo Lab works on the development of fluorescent enzyme-activated sensors that are used for imaging in guided cancer surgery and the targeting of viral proteases to create drugs for use during global pandemics. The lab believes in fostering an open, diverse, and inclusive environment for scientific research, welcoming researchers from all races, ethnicities, gender identities, sexual orientations, religions, educational backgrounds, and abilities, while also challenging systemic inequities in the field of science.
Focuses on Biomedical Data Science and informatics.