Dr. Bradley Moore

Biography

Dr. Moore's laboratory focuses on understanding the fundamental mechanisms and pathways involved in how microbes produce antibiotics, anticancer agents, and bioactive natural products, with a special emphasis on marine microorganisms. His research operates at the chemistry-biology interface and employs sophisticated approaches including heterologous biosynthesis, mutasynthesis, chemoenzymatic total synthesis, and both in vitro and in vivo biochemical analyses. Targeting marine microbes, his work has identified promising natural products like salinosporamide, didemnin, polyketide antibiotics, and neurotoxins such as domoic and kainic acid. By harnessing recombinant technology, he is aiding natural product discovery and expanding biosynthetic capabilities to yield new chemical entities and facilitate biological evaluation. Dr. Moore has made significant contributions through various honors, including the ASP Matt Suffness New Investigator Award and Fellow of the Royal Society of Chemistry. His teaching includes courses in Pharmaceutical Chemistry and Marine Natural Products.

Research Interests

Experience

Awards