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Dr. Faubert leads a research laboratory focused on understanding metabolic reprogramming, which refers to alterations in metabolic flux that support cancer cell survival, growth, and progression. His lab has extensive expertise in both in vitro and in vivo metabolic analyses, including the direct measurement of tumor metabolism in intra-operative settings with patients. To achieve a comprehensive understanding of the metabolic pathways in cancer, Dr. Faubert's team employs a wide array of mass spectrometry platforms alongside advanced methodologies such as stable isotope tracing, metabolomics, and metabolic flux analysis. These tools allow the lab to dissect metabolic programs driving malignant phenotypes at cellular and systemic levels. Complementing the biochemical techniques, the lab utilizes molecular imaging technologies to non-invasively monitor tumor metabolic states in vivo. This dual approach enables investigation of metabolic heterogeneity across different tumor types and stages. Recent work from Dr. Faubert’s laboratory explores the metabolic alterations that occur during the metastatic cascade, aiming to uncover novel vulnerabilities that can be targeted therapeutically.
Department of Philosophy