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Dr. Faubert leads a research laboratory focused on understanding metabolic reprogramming, specifically the alterations in metabolic flux within malignant cells that support cancer cell survival, growth, and progression. The Faubert lab has extensive expertise in both in vitro and in vivo metabolic analysis, utilizing direct measurements of tumor metabolism intra-operatively in patients. To achieve a comprehensive understanding of the metabolic pathways involved in cancer, Dr. Faubert's team employs a wide array of mass spectrometry platforms alongside advanced methodologies such as isotope tracing, metabolomics, and metabolic flux analysis. These tools allow the lab to dissect the metabolic programs driving malignant phenotypes at both cellular and systemic levels. Complementing biochemical techniques, the lab also uses molecular imaging technologies to non-invasively monitor tumor metabolic states in vivo. This dual approach enables the investigation of metabolic heterogeneity across various tumor types and stages. Recent work from Dr. Faubert’s laboratory explores the metabolic alterations that occur during the metastatic cascade, aiming to uncover novel vulnerabilities for therapeutic targeting.
Department of Philosophy