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Brenton Hoffman is an Associate Professor in the Department of Biomedical Engineering at Duke University. His research center focuses on understanding mechanotransduction across molecular levels and investigates how mechanical and chemical cues from the environment influence cellular responses that dictate physiological and patho-physiological outcomes, particularly in vascular biology. Employing an interdisciplinary approach, Hoffman's work combines protein engineering, molecular biology, biomaterials, automated image analysis, and live-cell microscopy. A key aspect of his research is the engineering of biosensors that allow for the dynamic measurement of tension in specific proteins within living cells. This innovative technology provides insights at the molecular scale and aligns with principles of molecular biology and biophysics. Additionally, Hoffman's educational contributions include a variety of courses that encompass aspects of cellular engineering and mechanotransduction, aimed at cultivating a new generation of engineers and researchers in biomedicine.
Duke University • Durham, NC
Teaching and conducting research in the field of Biomedical Engineering.
Department of Biomedical Engineering (MS program)