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Brian Hardy’s research focuses on pharmacokinetics and pharmacodynamics of drugs in the elderly. His clinical studies examine drugs used for major depression and bipolar disorder in elderly patients. As the aging population increases, the number of prescribed medications for elderly individuals significantly exceeds that of younger age groups. Hardy’s work emphasizes the need to modify dosages based on the pharmacokinetic and pharmacodynamic responses specific to older adults, given that standard studies often involve young, healthy volunteers. His research aims to identify how aging alters drug disposition and effectiveness, necessitating dose adjustments in medications for effective management of health conditions. By studying a range of elderly subjects, Hardy seeks to discern differences in drug effectiveness and side-effect profiles compared to younger populations. His findings include dosage modifications for drugs like lithium, aiming to optimize treatment for elderly patients experiencing conditions like major depression and bipolar disorder. Ultimately, his research is crucial for improving the therapeutic outcomes in older populations who require targeted medical interventions.
Department of Sociology