Dr. Brooke Hjelm

Biography

Brooke Erika Hjelm is an Assistant Professor in Clinical Cancer Biology at the Keck School of Medicine of the University of Southern California. Her research primarily focuses on the role of mitochondrial DNA in psychiatric conditions and cancer biology. Hjelm's investigations delve into how early life stress affects mitochondrial DNA copy number in medically healthy young adults, contributing to an understanding of the link between mental health and biological indicators. She has published numerous articles in peer-reviewed journals, including studies that highlight the distinct mitochondrial DNA deletion profiles related to pediatric cancers and the impact of cPLA2 activation in Alzheimer's Disease. Her work also encompasses the exploration of mitochondrial dysfunction in schizophrenia and bipolar disorder, aiming to elucidate the genetic underpinnings of these complex psychiatric disorders. Hjelm's commitment to advancing cancer biology and neuroscience is reflected in her multiple publications, which provide valuable insights into mitochondrial dynamics, signaling pathways, and genetic influences on neurological and psychiatric health.

Research Interests