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Bryan Grenfell is a population biologist working at the interface of theoretical models and spatio-temporal epidemiological data. His lab investigates the population dynamics of infectious diseases, focusing on the epidemiological and evolutionary dynamics of control and vaccination strategies. He is particularly interested in understanding the nonlinear spatio-temporal dynamics of acute immunizing infections and how they are affected by control strategies. His work has evolved from a focus on measles to include comparative dynamics of a range of pathogens, including influenza, rotavirus, RSV, non-polio enteroviruses, HIV, HCV, and veterinary morbilliviruses. The lab also explores phylodynamics, particularly how pathogen phylogenies are affected by host immunity and transmission bottlenecks at epidemic dynamics across scales, from individual hosts to population levels. In recent years, the dynamics of the COVID-19 pandemic have become a major focus of his research group, specifically modeling the immuno-epidemiological and evolutionary dynamics of SARS-CoV-2 and its implications for epidemic control. Recent studies have addressed the dynamics of measles in developing countries, the implications of vaccination refusal, the spatiotemporal dynamics of human influenza in the U.S., and the linking of within-host population dynamics to epidemiological outcomes in both human and animal influenza. He advocates for the establishment of a potential global immunological observatory to clarify epidemiological dynamics for future surveillance.
GRE scores are not accepted. Ph.D. is the primary degree; students are not required to hold an M.S.E. prior to admission.