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Carol J. Deutsch, Ph.D., is a Professor in the Department of Physiology at the Perelman School of Medicine, University of Pennsylvania. With extensive expertise in biophysics and physiology, Dr. Deutsch's research primarily focuses on the function and assembly of voltage-gated potassium channels, specifically Kv1.3 found in human T cells. Her lab investigates the roles that Kv1.3 plays in maintaining the resting membrane potential of T cells and mediating their volume regulation, which is critical for mitogen-stimulated T-cell proliferation. The research integrates various techniques, including electrophysiological assays and molecular biology methods, to understand the activation, inactivation, and recovery of Kv1.3 channels. Dr. Deutsch's contributions to the field are significant in elucidating the determinants of potassium channel conductance and their impact on immune cell function.
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