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Carole Ober's laboratory focuses on identifying genetic variants that influence gene expression in tissues relevant to complex phenotypes and common diseases, particularly asthma, chronic rhinosinusitis, and fertility. The lab utilizes freshly isolated cells, tissue cell culture models, and gene-environment interactions to dissect the genetic architecture of common diseases. Research studies are conducted with founder populations, including the Hutterites of South Dakota and Amish from northern Indiana in the United States, as well as European birth cohorts and various patient populations in Chicago.
Department of Philosophy