Dr. Caroline Zeiss

Biography

Caroline Zeiss is a Professor of Comparative Medicine with a joint appointment in the Department of Ophthalmology and Visual Sciences at Yale University. She served as Chief of Pathology in Comparative Medicine and directed the Pathology Research Core from 2005 to 2019. Dr. Zeiss is trained as both an anatomic pathologist and a laboratory animal veterinarian, specializing in comparative neuropathology and ophthalmic pathology, particularly concerning non-human primate pathology. Her research emphasizes the critical issues surrounding the translation of animal studies to human therapies, especially in the context of neurologic diseases such as Parkinson's and Alzheimer's. Dr. Zeiss employs applied biomedical informatics and natural language processing to enhance the evaluation of animal use patterns and their relationship to FDA approval processes. In addition, she is the Co-Director of the Alzheimer's Disease Research Center at Yale, focusing on comparative neuropathologic analyses of aging in primate brains. Her work has been recognized through multiple grants aimed at understanding the impacts of concurrent infections on health outcomes, particularly during the COVID-19 pandemic. Throughout her career, she has contributed significantly to veterinary education and served in various professional organizations.

Research Interests