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Charles Geoffrey Burns is an Associate Professor in Cardiovascular Research at Boston Children's Hospital. His lab specializes in understanding cardiovascular progenitor cells and their role in embryonic heart development across vertebrate species, particularly zebrafish. The lab focuses on the anterior heart field (SHF), crucial for the formation of the right ventricle and outflow tract, exploring how defects in SHF development can lead to congenital heart malformations such as Tetralogy of Fallot. Current research utilizes genetic and small molecule screening methods to discover regulators of SHF development and investigate the embryonic process of pharyngeal arch artery (PAA) development, which is vital for aorta and pulmonary artery formation. Additionally, Burns' research addresses the challenge of cardiac regeneration, seeking to identify pathways that could advance therapeutic methods for treating heart injuries by analyzing the regenerative capabilities of zebrafish hearts. His interdisciplinary approach integrates genetics, biology, and developmental studies to unveil novel insights in cardiovascular health.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).