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Charles Chavkin is the Allan Phyllis Treuer Endowed Chair in Pain Research at the University of Washington, specializing in the molecular mechanisms of drug addiction and the neurobiological foundations of motivated behavior. His research focuses on opioid receptor signal transduction, examining how various drugs, including heroin and cannabinoids, alter neuronal functioning and shape neural circuits responsible for motivation. Chavkin's lab employs integrative approaches to explore the effects of sustained opioid exposure on receptor desensitization and synaptic plasticity, contributing to our understanding of drug tolerance and addiction. He aims to generate targeted genetic changes in mice to study behavioral responses to drugs, such as opioids and cocaine, furthering insights into the neurobiological basis of addiction.
University of Washington • Seattle, WA
Leads research in pharmacology with a focus on the neurobiological basis of addiction and pain.
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