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Charles DeLisi is a Professor in Bioinformatics at Boston University, affiliated with the Physics department. His research is centered around the Bimolecular Systems Laboratory, where he develops and applies computational and mathematical methods in conjunction with high-throughput experimental techniques. His work involves analyzing changes in gene and protein expression profiles in response to endogenous and exogenous signals. Collaborating with the Fraunhofer Center for Manufacturing Innovation, DeLisi's team focuses on developing new DNA peptide microarray technologies for fingerprinting the complete molecular state of cells. His research encompasses determining how cells respond to various ligands, including drugs, toxins, and hormones, and the changes that occur in normal cells as they mature or progress towards disease states. Long-term, he aims to relate expression patterns and pathways to specific functions within cellular networks. Currently, his research also involves the application of experimental and computational methods for high-throughput genomic and proteomic analysis, especially in relation to cancer and immune reactions.
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