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Charles "Chuck" Williams is an Assistant Professor in the Department of Medicine at Michigan State University's College of Human Medicine. He is a translational scientist whose expertise bridges chemical biology, cell signaling, genetics, and developmental biology. Dr. Williams has made significant contributions to the scientific community, including elucidating the cell-autonomous responses of angioblasts to hedgehog signaling during artery specification. He played a pivotal role in characterizing the critical function of PDE4 in regulating hedgehog signaling and is credited with discovering a small molecule inhibitor of GPR68. Collaborating with Dr. Hong, his research focuses on the intricate roles of centrosome breakdown in myocytes within the context of human disease. Alongside Drs. Hong and Neitzel, Dr. Williams is at the forefront of developing innovative therapies targeting pivotal pro-oncogenic signaling pathways activated downstream of the Warburg Effect. His ongoing investigations include the exploration of extracellular acid signaling as a modality in disease development. Additionally, Dr. Williams has published several case reports and presented posters at various international and regional conferences, focusing on topics such as the mental health effects of COVID-19 in admitted patients and is currently preparing a manuscript for submission to JAMA.
Michigan State University • East Lansing, MI
Research in the Department of Medicine with a focus on translational science.
Department of Psychology