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Charlotte M. Mistretta is the William R. Mann Professor Emerita at the University of Michigan School of Dentistry. Her research focuses on the early development and differentiation of the taste system. Current projects in her laboratory investigate the developmental interactions among embryonic neurons from the geniculate, petrosal, and trigeminal ganglia and their sensory target organs on the tongue, specifically the taste papillae and resident taste buds. Additionally, her experiments address the role of neurotrophins in promoting neurite outgrowth and regulating the differentiation and neurophysiological properties of embryonic ganglion cells. Mistretta's work also explores the nature of molecular exchanges between the tongue epithelium and mesenchymal tissues during the formation of taste papillae, contributing to the understanding of neurite growth on the tongue.
Department of Electrical Engineering and Computer Science