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Chris Hanley graduated from Imperial College London with a BSc in Biochemistry in 2008, followed by an MRes in 2011 and a PhD in 2014, both from the University of Southampton, with a period of study at the University of Wisconsin-Madison. He has worked as a post-doctoral researcher at the University of Southampton's Cancer Sciences Unit and at the Johns Hopkins Centre for Cell Dynamics. Dr. Hanley's research focuses on understanding the tumor microenvironment and its influences on cancer progression, particularly the role of cancer-associated fibroblasts (CAFs). He utilizes advanced techniques such as single-cell RNA sequencing, digital pathology analysis, and 3D organotypic co-cultures integrating autologous tumor organoids with stromal cells. His significant achievements include the identification of NAD(P)H Oxidase 4 (NOX4) as a therapeutic target and subsequent development of NOX inhibitors for cancer treatment, which have led to clinical trials. He is currently leading and participating in several research projects aimed at understanding and targeting CAF functions in various cancers.