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Chris Mahony obtained his PhD from the University of Aberdeen and later gained postdoctoral experience at the Universities of Geneva and Birmingham. He has developed expertise in functional genomics, molecular biology, bioinformatics, and spatial transcriptomics, primarily focusing on unraveling the complexities of inflammatory diseases. His recent research centers on identifying novel transcriptional regulators that drive synovial fibroblast pathogenicity in Rheumatoid Arthritis, while also mapping the cellular landscape of inflamed joints in Juvenile Idiopathic Arthritis (JIA). His work integrates cutting-edge single-cell analysis techniques, spatial transcriptomics, and multiplex imaging to discover novel biomarkers and therapeutic targets, which are subsequently validated through various molecular biology approaches. Currently based at the University of Glasgow, Mahony's research aims to elucidate the intricate crosstalk between aging fibroblasts and immune cells, focusing on uncovering age-associated mechanisms contributing to immune-mediated inflammatory diseases (IMIDs) and their therapeutic resistance.