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Christian Simonsson's research aims to further the understanding of common liver diseases, particularly non-alcoholic fatty liver disease (NAFLD), by employing combination systems biology modeling and multi-modal MRI techniques. NAFLD is characterized by excessive fat storage in the liver, which can lead to serious health risks, including chronic inflammation known as non-alcoholic steato-hepatitis (NASH). Chronic NASH can cause liver damage and induce fibrosis, which can progress to cirrhosis— a condition that severely impairs liver function and requires liver transplantation for treatment. Simonsson emphasizes the growing prevalence of NAFLD and the necessity for precise non-invasive clinical methods to detect disease progression early. His PhD project aims to conduct clinical studies to collect data related to NAFLD, utilizing various MRI techniques to refine measurements pertinent to the disease. By integrating diverse data types, including animal models and micro-physiological systems, he aims to construct systems biology models to elucidate the mechanisms behind the development and progression of NAFLD and NASH.
Requirements are standardized across the Faculty of Science and Engineering (Institute of Technology) for international Master's programs.