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Christina Castellani is an Assistant Professor with a cross-appointment in the Department of Epidemiology and Biostatistics at Western University. With an MSc and PhD from Western University and a Postdoctoral Fellowship from Johns Hopkins University School of Medicine, Dr. Castellani's research focuses on cardiovascular disease and mitochondrial DNA. Her lab investigates mitochondrial nuclear multiomic signaling's contribution to cardiovascular disease, utilizing bioinformatic and cell culture approaches. Key areas of her research include the integration of large-scale multiomic datasets to determine relationships between mitochondrial DNA copy number and various genomic patterns, developing models to modify mitochondrial DNA copy number and heteroplasmy, and assessing the impact of environmental stimuli on mitochondrial DNA signaling. The Castellani Lab actively seeks undergraduate and graduate students for research opportunities.
Streams include Archaeology and Bioarchaeology, and Sociocultural Anthropology.