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Christopher Burge is a prominent professor in the Department of Biology at the Massachusetts Institute of Technology, known for his innovative research in the field of gene regulation and RNA splicing. He employs a combination of experimental and computational methods to decode the regulatory codes that govern pre-mRNA splicing and post-transcriptional gene regulation. His expertise extends to studying the specific locations of intron splice sites within primary transcripts and how these locations can change across different cell types. Burge's lab aims to map RNA-binding affinity spectra for dozens of human RNA-binding proteins, integrating this with in vivo binding activity data to understand the functional roles of 3’ untranslated regions and their contributions to mRNA localization and microRNA regulation. His work has significant implications for understanding the complexities of gene expression and regulation at the molecular level.
Massachusetts Institute of Technology • Cambridge, MA
Leads research on gene regulation and RNA splicing.