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Christopher Chang's research focuses on the intersection of chemistry and biology, with a significant emphasis on developing new imaging and proteomics techniques for drug discovery and catalysis. His innovative work includes the development of activity-based sensing platforms to identify various metal ions and reactive species, which are crucial for understanding protein functions and the mechanisms of diseases such as neurodegeneration and cancer. He explores the roles of essential nutrients like copper and iron as signaling molecules that regulate protein function and metalloallostery. Chang has pioneered methods to detect reactive oxygen and sulfur species, further elucidating their roles in cancer metabolism and immune response. His research also delves into single-atom signaling, seeking to comprehend the reversible modifications on proteins and their implications for drug development. Overall, his contributions are vital in advancing new concepts in chemical biology and therapeutic innovations aimed at treating complex diseases.
GRE scores are not accepted. Ph.D. is the primary degree; students are not required to hold an M.S.E. prior to admission.