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Clare Smith is an Assistant Professor in the Department of Molecular Genetics and Microbiology at Duke University and a member of the Duke Human Vaccine Institute. Her lab focuses on understanding host genetic diversity, bacterial variation, and the genetic interactions between hosts and pathogens that drive tuberculosis disease states. Utilizing systems genetics and cutting-edge approaches, the Smith Lab investigates the genetic requirements of bacteria for growth and adaptation in diverse host environments, employing mammalian resources such as wild-derived mouse strains and the Collaborative Cross BXD. On the intersection of host and bacterial genome-wide approaches, her research aims to uncover critical interactions that underlie tuberculosis pathogenesis, drug treatments, and vaccine interventions.
Duke University • Durham, NC
Research and teaching in the Department of Molecular Genetics and Microbiology focusing on host-pathogen interactions related to tuberculosis.
Department of Biomedical Engineering (MS program)