Dr. Clifford Slayman

Biography

Clifford Slayman is Professor Emeritus at the Yale School of Medicine, specializing in Cellular and Molecular Physiology. His research primarily focuses on the physical aspects of membrane transport processes, particularly phenomena related to charge transport. He investigates proton pumps, proton-coupled cation transporters, and potassium channels in plasma membranes of fungi, including Saccharomyces cerevisiae and Candida albicans. His work employs site-directed mutagenesis and heterologous expression to analyze functional differences in analogous proteins across species. Slayman has contributed to understanding mechanisms of small cationic peptides (RAMPs) produced by a variety of plant and animal cells, which have implications for developing new therapeutic drugs. His interests also extend into the chemistry of morphogenetics and autophagy in fungi. With a robust publication record, Slayman's contributions have significantly enriched the field of physiology and membrane biology.

Research Interests