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Colin Crist is an Associate Professor in the Department of Human Genetics at McGill University. His research focuses on the molecular mechanisms that govern skeletal muscle stem cell activity and the role of microRNAs in maintaining tissue identity. His work addresses the challenges of skeletal muscle disorders, such as muscular dystrophies and muscle wasting associated with aging and cancer. Crist employs molecular biology techniques to explore how muscle stem cells (MuSCs) respond to environmental cues, adapt, and make critical decisions about self-renewal and differentiation. He investigates the contribution of microRNAs to cell fate decisions and is focused on developing stem cell-based regenerative therapies for muscle diseases. His lab seeks to identify targetable pathways and small compounds that enhance the regenerative potential of muscle stem cells, thereby improving therapeutic outcomes.
Department: Department of Medicine. Program: Experimental Medicine.