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The Corey Laboratory at Harvard Medical School focuses on the gating of mechanically sensitive ion channels and the role of these channels in vertebrate hair cells within the inner ear. Research centers on the intricate mechanics of hair cells, which are the receptor cells that respond to sound and acceleration. The lab studies how mechanical deflection of hair bundles influences tension on tip links, which are essential for the opening of force-gated transduction channels. Additionally, the lab explores the structure, biophysics, and function of the proteins involved in mechanosensation, seeking to understand the sensory transduction process at an atomic level. The research also delves into deafness associated proteins and the development of novel gene therapy methods, particularly for treating hereditary deafness, including Usher syndrome, which causes both deafness and blindness. Through ongoing group projects, the lab aims to devise strategies for clinical application of these therapies.
Administered by the Division of Medical Sciences (DMS). GRE is not required and will not be considered for BBS, Immunology, and Neuroscience.