Dr. Crystal Mackall

Professor

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Biography

Crystal L. Mackall, M.D., is the Ernest Amelia Gallo Family Professor in the Department of Pediatrics at Stanford University. She is the Founding Director of the Stanford Center for Cancer Cell Therapy and the Co-Leader of the Stanford Cancer Immunotherapy Program. Her career spans decades of internationally recognized translational research focused on immune-oncology, advancing the understanding of fundamental immunology and its translation into treatments for human diseases, particularly in pediatric cancers. Dr. Mackall has led numerous first-in-human clinical trials, including innovative therapies using genetically engineered T cells. Her pioneering work established the essential role of IL-7 in T cell homeostasis and has led to significant advancements in CAR T cell therapies. Additionally, she is an active member of several prestigious organizations and has received multiple awards for her contributions to oncology research.

Research Interests

Experience

Professor

2016-01-01 — Present

Stanford University • Stanford, California

Leading a research group focused on cancer immunotherapy and T cell regeneration.

Awards

#2025

Lloyd Old Award

2025-01-01
#2021

Smalley Award

2021-01-01
#2021

AACR-St.Baldrick’s Distinguished Achievement Award

2021-01-01

Patents

Anti-CD22 Chimeric Antigen Receptors

61/549,516 2018-01-01

Patent pending on CAR technology for targeting CD22.

M971 Chimeric Antigen Receptors

61/717,960 2018-01-01

Patent pending for chimeric antigen receptors.

Anti-CD276 polypeptides, proteins, and chimeric antigen receptors

61/805001 2018-01-01

Patent pending on CAR targeting CD276.

Courses

BIOPHYS 300 CBIO 399 IMMUNOL 399 STEMREM 399 MED 370 BIO 199X IMMUNOL 199

Requirements for Stanford University

Doctorate Program
Requirements
GPA Requirement
Required:3.5
TOEFL
Listening
Required:26
Reading
Required:26
Writing
Required:26
Speaking
Required:26
Total
Required:100
GRE General
Verbal
Required:160
Quantitative
Required:165
Analytical Writing
Required:4.5
Overall
Required:4.5
Prerequisites
Bachelor degree from an accredited institution Strong background in mathematics and programming
Application Checklist
  • Statement of Purpose
  • Three letters of recommendation
  • Official transcripts
  • Resume/CV
Specialization Notes

The Computer Science department emphasizes research potential. GRE General is currently optional but recommended for some tracks.