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Daniel Beard is the Carl J. Wiggers Collegiate Professor in Biomedical Engineering at the University of Michigan. His research focuses on cardiac energy metabolism, exploring the primary pathways that regulate mitochondrial ATP synthesis in the heart. Dr. Beard's lab has made significant contributions by discovering that inorganic phosphate serves as a crucial feedback signal controlling the rate of oxidative phosphorylation in the heart, challenging entrenched theories about how cellular energetic states are maintained. Current research is centered on understanding how control of energy metabolism can break down in heart failure, with particular attention to the loss of specific cytoplasmic pools that disrupt energetic states and mechanical function during heart failure. Additionally, his work examines oxidative metabolism and energetics in skeletal muscle, the regulation of coronary blood flow, and the etiology of hypertension, developing theoretical and computational models to elucidate the mechanisms controlling arterial pressure and guide experimental designs. Dr. Beard has multiple appointments across various departments, reflecting his broad expertise in physiology and medicine.
University of Michigan • Ann Arbor, MI
Serves as a faculty member and conducts research in cardiac energy metabolism.
Department of Electrical Engineering and Computer Science