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Daniel L.M. Suess is an Associate Professor in the Department of Chemistry at the Massachusetts Institute of Technology. His research focuses on understanding the molecular chemistry that underlies global biogeochemical cycles and aims to leverage this knowledge to improve human health and positively impact the environment. The Suess Lab addresses challenges at the interface of inorganic and biological chemistry, particularly examining reactions catalyzed by metalloenzymes. These metalloenzymes often contain active sites with single metal ions or polynuclear metallocofactors, which are clusters of multiple metal ions that work together to enhance catalytic efficiency. Iron-sulfur clusters, a type of polynuclear metallocofactor, play crucial roles across various life processes, influencing metabolism and the molecular makeup of the biosphere. The lab investigates the mechanisms of reactions involving iron-sulfur clusters, with a focus on elucidating the fundamental chemical bonds responsible for their unique reactivities. By studying both synthetic and biogenic iron-sulfur clusters, the lab seeks to deepen understanding of the relationship between their structures, reactivity, and overall functions in biological systems.