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Daniela Rotin is a Professor in the Department of Biochemistry at the University of Toronto and a Senior Scientist in the Cell Biology Program at Hospital for Sick Children. She completed her PhD under Dr. Ian Tannock at the Ontario Cancer Institute in Toronto. Following her doctoral studies, Dr. Rotin pursued postdoctoral fellowships, focusing on ion transport and signal transduction. Her research primarily investigates the ubiquitin system, specifically the Nedd4 family of E3 ubiquitin ligases, and their roles in various physiological processes and human diseases, including cystic fibrosis, Inflammatory Bowel Disease, and cancer. Dr. Rotin has developed innovative proteomic methodologies to identify substrates of E3 ubiquitin ligases in cells and model organisms. Her contributions to the field include detailed studies on membrane proteins and the analysis of pathogenic variants associated with human diseases. She teaches courses on Eukaryotic Signaling at the University of Toronto and has received numerous awards for her research contributions, including a Fellowship from the Royal Society of Canada.
Department of Sociology