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Dario De Jesus is an Assistant Professor in the Biological Sciences Division at the University of Chicago. His research focuses on the roles of m6A methylation in various metabolic processes, particularly in adipose tissue and pancreatic cells. His notable works include investigating how METTL14 regulates early pancreatic cell differentiation and how brown fat m6A methylation affects systemic insulin sensitivity. De Jesus has published extensively in high-impact journals like Nature Communications, EMBO Journal, and Cell Metabolism, contributing to a better understanding of metabolic regulation and insulin secretion. He is known for his innovative use of fluorescein-based sensors to study human a-cells and how metabolic enzyme deficiencies can lead to conditions like hypoglycemia and non-alcoholic fatty liver disease (NAFLD). His commitment to uncovering the intricate molecular mechanisms underlying these processes highlights the significant interplay between RNA methylation and metabolism. Through his research, he aims to advance the field of metabolic diseases and identify potential therapeutic targets.
Department of Philosophy