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David Alagpulinsa is an Assistant Professor at Yale School of Medicine focusing on Comparative Cardiovascular Medicine as a core member of the Yale Center for Molecular & Systems Metabolism. His research program integrates human genetics and single-cell multi-omics to explore how the hematopoietic system connects autoimmune, cardiometabolic, and neurocognitive diseases through shared genetic and molecular pathways. He earned his PhD in Interdisciplinary Biomedical Sciences from the University of Arkansas for Medical Sciences, where he investigated mechanisms for maintaining genetic integrity in cancer, using multiple myeloma as a model. As a postdoctoral fellow at Massachusetts General Hospital and Harvard Medical School, he expanded his focus to autoimmune diseases, developing strategies to immunoprotect transplanted pancreatic islets to treat type 1 diabetes without systemic immunosuppression. In 2023, he established AlagsLab at Yale, an interdisciplinary research group aimed at dissecting the genetic regulatory architecture of type 1 diabetes and its pleiotropic links to neurocognitive and cardiovascular traits, integrating statistical and molecular genetics with experimental models to advance precision therapies.
Massachusetts General Hospital & Harvard Medical School • Boston, MA
Focused on developing strategies to address autoimmune diseases and associated metabolic conditions.
Administered via the Graduate School of Arts and Sciences (GSAS). GRE General is optional for PhD.