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David E. Cane is the Vernon K. Krieble Professor Emeritus of Chemistry and Molecular Biology, Cell Biology, and Biochemistry at Brown University. His academic journey began with undergraduate studies at Harvard, where he later earned a Ph.D. in 1971 under the mentorship of Prof. E. J. Corey. He has cultivated a focused interest in organic synthesis, especially regarding natural product biosynthesis and bioorganic chemistry. He has developed significant methodologies for enzyme characterization, which have elucidated details about cyclization processes in terpenoid biosynthesis. Prof. Cane's collaborative efforts have advanced the understanding of biosynthetic pathways for various antibiotics, including erythromycin, employing synthetic, enzymological, and molecular genetics techniques. His research group has made notable contributions in mechanistic enzymology and molecular genetics, particularly in the realms of polyketide antibiotic biosynthesis and terpenoid metabolism. Recognized for his scientific contributions, he is a fellow of the American Association for the Advancement of Science and the American Academy of Arts and Sciences, among others. Prof. Cane has published over 330 scientific publications and has a rich history of leadership roles in editorial boards and professional committees.
Brown University • Providence, RI
Leading research in the fields of chemistry and biochemistry with a focus on natural products biosynthesis.
Department: Department of Economics