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David R. Lynch is a Professor in the Department of Neurology at the Perelman School of Medicine at the University of Pennsylvania. He earned his B.S. in Molecular Biophysics and Biochemistry from Yale College in 1981, followed by an M.D. in Neuroscience and a Ph.D. in Neuroscience from Johns Hopkins University in 1988. His research expertise focuses on NMDA receptors and excitotoxicity, highlighting their significant roles in cerebral ischemia and neuronal damage due to prolonged seizures. Lynch's work considers the neuroprotective properties of NMDA receptor antagonists and their applications in treating human diseases. By investigating the physiological and pharmacological properties of NMDA receptor subtypes, he aims to develop therapeutic agents that can selectively target these receptors. His studies have revealed the complex behavior of different NMDA receptor subtypes in relation to intracellular calcium changes and excitotoxic processes. Lynch's innovative approach combines molecular biology techniques and systematic examination of receptor properties to advance the understanding of excitotoxicity and potential treatments for related disorders.
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