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David Paterson is a leading researcher in cardiac neurobiology, focusing on the cardiac autonomic nervous system and its communication with end organs. His team has established that oxidative stress plays a significant role in the uncoupling of pre-synaptic and post-synaptic signaling. They have developed methods to target enzymes involved in the production of nitric oxide-cGMP by using gene transfer approaches with cell-specific viral vectors and FRET sensors to investigate messenger physiology in both normal and diseased hearts. His work applies human induced pluripotent stem cell 'disease dish' models involving sympathetic neurons and cardiac cells to study cardiac pathologies and diseases related to the autonomic nervous system. He completed his D.Phil at New College, University of Oxford in 1989 and has held faculty positions at various reputable institutions, including a full professorship in physiology since 2002. Paterson has received recognition for his contributions through numerous awards and memberships in prestigious organizations, including the Royal Society Biology and American Physiological Society. He has also served in editorial roles for major physiology journals and has been actively involved in leadership positions in academic committees and research assessments.
University of Oxford • Oxford, England
Leading researcher in cardiac neurobiology and head of the Department of Physiology, Anatomy & Genetics.
University of Oxford • Oxford, England
Establishing faculty post focusing on cardiac physiology.
University of Oxford • Oxford, England
Promoted to Reader with a focus on cardiovascular physiology.
Department of Politics and International Relations - Higher Level English requirement.