Dr. David Schatz

Biography

David G. Schatz is a Waldemar Von Zedtwitz Professor of Immunobiology at Yale School of Medicine, where he holds a dual appointment in Molecular Biophysics and Biochemistry. He has made significant contributions to understanding the mechanisms that assemble and diversify antigen receptor genes that encode antibodies and T cell receptors. His groundbreaking discovery of RAG1 and RAG2 has led to important biochemical insights regarding their function and evolutionary origins. Schatz has co-authored over 180 articles in prestigious scientific journals and has received numerous accolades, including the Paul Ehrlich Ludwig Darmstaedter Prize and election to both the National Academy of Sciences and the National Academy of Medicine. He is actively involved in editorial responsibilities and has served as the Director of Graduate Studies in Immunobiology, demonstrating a strong commitment to graduate education. His research focuses on the processes that generate diversity within the immune system, including V(D)J recombination and somatic hypermutation, linking these processes to the development of B cell cancers. Schatz has also explored the evolutionary origins of RAG proteins, advancing the understanding of their role in adaptive immunity.

Research Interests

Experience