Dr. David Stern

Biography

David F. Stern earned a Bachelor of Science in Biology from the Massachusetts Institute of Technology in 1976 and a PhD in Biology from the University of California, San Diego in 1983. His dissertation research elucidated the coronavirus lytic cycle. After postdoctoral work in R.A. Weinberg’s lab at MIT Cancer Center and Whitehead Institute, which focused on the analysis of the neu/ErbB2/HER2 oncogene, he joined the Yale Pathology faculty in 1988. Dr. Stern’s research primarily investigates the roles of growth factors and receptors in malignant transformation, with a particular emphasis on breast cancer. His work on the receptor tyrosine kinase ErbB2/HER2, which drives approximately 25% of breast cancers, is notable as it has contributed significantly to understanding DNA damage response and resistance mechanisms in cancer therapy. He is also actively involved in the Yale Cancer Center, providing scientific leadership as the Associate Director of Shared Resources.

Research Interests