Dr. David Stuart

Biography

David Stuart is a Professor and Graduate Coordinator in the Department of Biochemistry at the University of Alberta. He received his Ph.D. from the University of Alberta and has extensive expertise in the regulation of cell division and differentiation processes. His research primarily focuses on the mechanisms regulating cell division driven by Cyclin-Dependent Protein Kinases (CDKs) and their regulatory subunits, cyclins. Stuart's work has highlighted how inappropriate activation of cyclin/CDK complexes can lead to unregulated cell division and tumor formation. His current research projects include the regulation of meiotic cell cycle progression, the initiation of DNA replication by Cyclin/CDK complexes, and the regulation of meiotic gene expression, particularly in the context of nutrient deprivation in yeast cells. Additionally, he applies synthetic biology and metabolic engineering approaches for biofuel and bioproduct synthesis, engineering yeast strains for the production of various alcohols and fatty acids. Furthermore, Stuart investigates the composition and regulation of repressor complexes containing Histone Deacetylases and their role in cellular differentiation. His work aims to understand cell division regulation mechanisms and contribute to developing therapies for proliferative disorders.

Research Interests

Experience