Dr. David Thompson

Biography

Professor David Thompson specializes in Organic Chemistry with a focus on the development of plasma-stable liposomes for efficient intracellular drug delivery. His research addresses the challenges of liposome-based formulations, particularly the inefficient escape of encapsulated contents. He has developed systems that enhance membrane permeability, utilizing acid-catalyzed photooxidative cleavage reactions to improve the release of water-soluble drugs, photosensitizers, and plasmids into target cells. His laboratory investigates novel lipid membrane constructs for various applications, including 1) templates for two-dimensional protein crystallization, 2) biomimetic energy transduction mechanisms using bolaamphiphile membrane vesicles, 3) supported bilayer membrane sensors, and 4) the creation of controlled-release polymer hydrogels. Thompson’s education includes a B.S. & B.A. in Chemistry & Biology from the University of Missouri-Columbia and a Ph.D. in Organic Chemistry from Colorado State University. He has received accolades such as the University Faculty Scholar award in 2006, and served as a visiting professor at the University of British Columbia's Department of Biochemistry in 1992.

Research Interests