Generate a tailored SOP for Dr. David Uehling. Improve your application with a focused, well-structured draft.
David Uehling is an Assistant Professor at the Leslie Dan Faculty of Pharmacy, University of Toronto. His research focuses on drug development and disease diagnostics, specifically in the area of drug safety and understanding the molecular basis of drug targets and diseases. Uehling is particularly interested in developing small molecule inhibitors that disrupt protein-protein interactions and in proximity-inducing agents. His research addresses the challenges in identifying cell-permeable drugs that bind to previously unvalidated biological targets and influence their function, especially for classic targets that have not been successfully drugged. He employs bioinformatics and machine learning approaches to prioritize promising targets and identify drug leads. Uehling has led chemistry teams during his tenure at GlaxoSmithKline, where he contributed to the discovery of drugs such as lurtotecan and dabrafenib, and he played a crucial role in identifying drugs targeting novel protein-protein interactions at the Ontario Institute for Cancer Research. His significant work has spurred collaborative partnerships with the pharmaceutical industry.
Department of Sociology