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David M. Waisman is a professor in the Department of Biochemistry & Molecular Biology at the Cumming School of Medicine at the University of Calgary. He has a rich research background focusing on the biochemical and cellular biology aspects of plasmin, an enzyme crucial for blood clot lysis and its implications in pathological processes such as tumor growth and metastasis. His recent investigations delve into the role of annexin II heterotetramer, a multifunctional Ca2+-binding protein, in regulating plasmin production and activity. Waisman employs a variety of methodological approaches to understand the mechanisms through which annexin II contributes to the metastatic potential of cancer cells. This includes exploring its role in tumor cell-activated fibrin turnover and studying intracellular functions related to the actin cytoskeleton. His work aims to elucidate the structural regions of plasmin fragments, particularly angiostatin, that are involved in the tumor-killing activity, thereby advancing the knowledge in the field of cancer biology and therapeutic applications.
Department of Computer Science Master's program. GRE scores are expected for international students.