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David Weliky is a professor in the Department of Chemistry at Michigan State University. His research focuses on biophysical chemistry, specifically studying the mechanisms of viral entry into cells. He employs various biophysical methods, including nuclear magnetic resonance (NMR) spectroscopy, to investigate the structures and dynamics of viral proteins, such as the HIV gp41 and the influenza HA2 fusion proteins. Through his investigations, Weliky aims to contribute to a deeper understanding of membrane fusion processes, which are essential for the entry of enveloped viruses—including HIV, influenza, and others—into host cells. His laboratory combines approaches from molecular biology, protein expression, and NMR methodologies to analyze protein structures and dynamics in membrane environments. He has made significant contributions to the development of solid-state NMR techniques and applies them to study protein aggregation and interactions.
National Institutes of Health •
Department of Psychology